We analyzed previously published HCC data sets [20] that contain SIRT7 expression and detailed survival information; the Kaplan–Meier analysis revealed that patients with high SIRT7 expression levels in liver cancer tissues had significantly shorter overall survival rates than those with low SIRT7 expression (p = 0.008, Fig. 1f). The gene discussed is SIRT7; the disease is hepatocellular carcinoma.