AGT and Hypertension: Recent research demonstrated that XJEK formula has a protective effect against Nω-nitro-L-arginine methyl ester (L-NAME)-induced hypertension and angiotensin II (Ang II)-induced Human umbilical vascular endothelial cells (HUVECs) injury [16, 17], but the effect of polysaccharides from XJEK decoction on these two models has not been elucidated.