MYOM2 and dilated cardiomyopathy: Previous studies have reported that over expression of EH-myomesin (MYOM2 isoform) served as a biomarker for dilated cardiomyopathy and TNF-α was up-regulated during brief myocardial ischemia, or coronary occlusion (Zingarelli et al., 2002; Kimura et al., 2006).