One cluster, in common for both viruses, was characterized by increased type-2 and type-17 immune mediator (IL-4, IL-5, IL-13, IL-17, IL-20, IL-23, IL-33, and TSLP, a key regulator of asthma development) release, and it was linked to a higher risk of recurrent wheezing. This evidence concerns the gene IL5 and asthma.