NUCB2 and obesity due to melanocortin 4 receptor deficiency: By the injection of Nesfatin-1 in the hindbrain, Ze-Feng Xia et al. [64] found that the T-type calcium channel induced calcium ions influx in DMNV (dorsal motor nucleus of the vagus) neurons, which inhibited the process of feeding by exciting the vagus nerve in the body and inhibiting gastric acid secretion to reduce obesity.