In cultured IEC-6 cells, HuR silencing by transfection with siHuR also decreased cellular NPM levels, whereas ectopically expressed HuR by infection with the recombinant adenoviral plasmids containing human HuR complementary DNA (cDNA) (AdHuR) increased the levels of NPM (Figure 4B). The gene discussed is ELAVL1; the disease is infection.