DCC and SOX5 (which jointly functions with SOX6 in chondrogenesis) have been associated with chronic back pain [92], GABRB3 (encoding one of three beta subunits of the GABA A receptor along with GABRB2) has been associated with migraine and fibromyalgia [10], and ASTN2 and SLC24A3 have been associated with migraine [10,93]. This evidence concerns the gene ASTN2 and migraine disorder.