CDH1 and posterior cortical atrophy: One group found that α-Solanine, a naturally glycoalkaloid extracted in nightshade (Solanum nigrum Linn), remarkably stimulated E-cadherin expression while it concurrently attenuated vimentin and matrix metalloproteinase (MMP) expression, indicating that it blocked EMT and inhibited the viability and motility of human PCa cells.22