The CPSP-type neuropathic pain was completely abolished in LPA1- and LPA3-KO mice, as seen in the case with partial sciatic nerve injury-induced neuropathic pain model, though the peripheral neuropathic pain only shows the hyperalgesia on the ipsilateral side (Inoue et al., 2004, Ma et al., 2009). Here, LPAR3 is linked to Pain.