The mean serum levels of ALT & AST were significantly reduced in C. Sempervirens 300, C. Sempervirens 600, P. Ginseng 250, P. Ginseng 500, N. Sativa 500, N. Sativa 1000 and silymarin groups compared to AFB1 induced HCC group (P value < 0.0001). This evidence concerns the gene GPT and hepatocellular carcinoma.