F8 and stroke disorder: Considering that our patient had severe HA and a history of bilateral knee replacement due to spontaneous bleeding with a low CHA2DS2-VASc score for chance of stroke and we only used a single LIMA bridge and an annuloplasty ring for MVP, his lowest FVIII activity after 1000 IU FVIII replacement therapy every other day was 8.1%, thus we came to the conclusion that 100 mg aspirin alone per day was suitable postoperatively.