STX1A and diabetes mellitus: However, the comparison done by regression analysis, performed with Shesis software, adjusting for age, gender, diabetes status, waist circumference, total cholesterol, LDL, and HDL fractions as covariates, highlighted a significant association of Stx-1A rs4717806(A) and rs2293489(T) minor alleles with IHD risk (Pc = .02; OR: 2.43, 95%CI:1.1–5.3 and, Pc = .02; OR: 2.86, 95%CI:1.3–6.4, respectively) (Table 4) No association was found with the major allele.