After the ip administration of a single dose of 10 mg/kg RANCE‐1 followed by time lapse blood collection and terminal tissue collection in xenograft Caki‐1 tumor bearing NOD.CB17‐Prkdc SCID/J mice, it was determined that the compound was absorbed slowly, as indicated by a peak plasma concentration of Ru reached at 10 h after dosing. The gene discussed is PRKDC; the disease is neoplasm.