Therefore, to further explore the influence of PACAP-mediated signaling on the neurotrophin signaling pathway as another modulator of the innate immune response, we analyzed the expression of BDNF and neurotrophin receptors (p75NTR, TrkA, TrkB, and TrkC) in peritoneal exudate cells upon acute infection (Figure 5B). The gene discussed is ADCYAP1; the disease is infection.