CCL2 and macular retinal edema: Interestingly, it has been reported that the intraocular levels of monocyte chemoattractant protein-1 (MCP-1) (a chemokine), intercellular adhesion molecule-1 (ICAM-1) (an adhesion molecule), and interleukin-6 (IL-6) and IL-8 (inflammatory cytokines) are increased in BRVO patients with macular edema [20–24].