PIK3CA and neoplasm: Other driver mutations identified in one or two tumors (30 other genes identified, see Supplementary Figure 1) included NOTCH3, SMO, PIK3CA, and BRCA2. Of note, no driver mutations in the paired cohort were identified for TERT, SMARCB1, or BAP1. There were no differences by presence of a specific driver mutation in regard to patient sex, location of tumor, or grade of resection.