To reach this objective, we performed a search on PubMed, Medline, and Google Scholar for articles in English published up to May 2018 using the following keywords: oxidative stress, antioxidants; catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GTPx), reactive oxygen species (ROS), reactive nitrogen species (RNS), lipid peroxidation, paraoxonases (PONs), urinary bladder cancer, and nitric oxide. This evidence concerns the gene SOD1 and urinary bladder cancer.