COL8A1 and age-related macular degeneration: Meta-analysis of advanced AMD confirmed previously found associations to advanced AMD [24], while in contrast, Yang et al.'s study including 300 cases with nAMD, 300 cases with PCV, and 300 control subjects did not show the association of COL8A1 rs13095226 with nAMD or PCV, suggesting that this variant may not be a risk factor for nAMD or PCV in Chinese subjects [75].