To search for a biomarker related to tumorigenesis, we got 11 overlapped DEGs (CDH3, KRT80, ETV4, ESM1, FOXQ1, CLDN1, NFE2L3, LRP8, TEAD4, TRIB3, and WNT2) from 181 upregulated DEGs related to colorectal cancer development in our previous report (Figure 1(b)) and the top 20 upregulated DEGs in this analysis. The gene discussed is LRP8; the disease is colorectal cancer.