By Alizarin staining, we did not observe a sufficient difference in mineralization between two conditions OM and IL-1β (Figure 4), whereas by qPCR, we noted that IL-1β when used at 50 pg/ml concentration in osteogenic medium may increase osteopontin expression in BMC and FC at day 14 and day 7, respectively. This evidence concerns the gene IL1B and ocular melanoma.