Since A549 and THP-1 cell lines express a diverse set of HLA-I alleles (A549: A*25:01, A*30:01, B*18, B*44:03, C*12:03, C*16:01, and THP-1: A*02, B*15, C*03) (17, 18), we next assessed how different HLA-A, -B, and C allotypes are downregulated during influenza infection. This evidence concerns the gene HLA-A and influenza.