Our previous study also identified ubiquitin-proteasome, and that its proteasome subunit alpha type 2 was nitrated in pituitary adenomas, which affected the function of the proteasome that is a multicatalytic proteinase complex in the cytoplasmic and nuclear regions and is involved in an intracellular, ATP/ubiquitin-dependent, nonlysosomal proteolytic pathway (26). Here, RPS27A is linked to pituitary gland adenoma.