Similarly, 12 weeks of aerobic exercise have also been reported to result in improved cardiometabolic risk factors (waist circumference, insulin resistance, and lipid profile) together with increased circulating omentin levels in overweight/obese men (Saremi et al., 2010), which has been corroborated in later studies (Wilms et al., 2015; Ouerghi et al., 2017). This evidence concerns the gene ITLN1 and Insulin resistance.