AGT and metabolic dysfunction-associated steatotic liver disease: Several studies have shown a mechanistic role of RAS and AngII on hepatic fibrosis (Yoshiji et al., 2001; Yokohama et al., 2004), while those reporting the effect of ARB on NAFLD in murine models did not elucidate the underlying mechanisms (Sugimoto et al., 2006; Sturzeneker et al., 2011; Kato et al., 2012).