CXCR4 and atherosclerosis: Using cell-specific genetic ablation of CXCR4, endothelial CXCR4 has been shown to promote re-endothelialization after vascular injury and prevent neointimal hyperplasia (Noels et al., 2014) and to limit atherosclerosis development by maintaining the endothelial integrity (Döring et al., 2017).