Taken together, the lower markers of lipid and protein peroxidation (Dzik et al., 2018) attenuated atrophy in the paraspinal muscle (Bang et al., 2018), combined with decreased serum CRP, IL-6 and TNF-α levels and reduced the VAS score in the current study, suggesting that LBP patients supplemented with vitamin D have a better and faster possibility of recovery with reduced pain intensity. Here, IL6 is linked to Low back pain.