For example, the irreversible non-selective MAOIs tranylcypromine, the selective MAO-A inhibitors such as the irreversible inhibitor clorgyline and the reversible inhibitor moclobemide are used to treat depression and anxiety (for structures, see Figure 2; Riederer et al., 2004b; Tzvetkov et al., 2017). Here, MAOA is linked to depressive disorder.