The target genes of the inhibitor, identified by microarray analysis, included p21, p53, ubiquitin C, ZBED8, MDM2, CASP3, and FZD1 (Suebsoonthron et al., 2017), thereby explaining the enhanced sensitivity of the malignant NB cell lines to chemotherapy after Wnt signaling inhibition. This evidence concerns the gene TP53 and neuroblastoma.