Our CVD nomogram has 5 components: age, IL-6 and APN levels, DBP, and dyslipidemia, with a predictive ability higher than that of the Framingham study (AUC approximately 0.80) [31] and the simple model for a 10-year risk assessment program for ischemic cardiovascular disease in Chinese (AUC = 0.796) [32]. The gene discussed is IL6; the disease is metabolic syndrome.