Six genes are related to WS, including PAX3 (paired box gene 3, OMIM #606597), MITF (microphthalmia‐associated transcription factor, OMIM #156845), SNAI2 (snail homolog 2, OMIM #602150), EDN3 (endothelin‐3, OMIM #131242), EDNRB (endothelin receptor type B, OMIM #131244), and SOX10 [SRY (sex determining region Y)‐box 10, OMIM #602229], which are located on chromosomes 2, 3, 8, 13, 20, and 22, respectively. The gene discussed is PAX3; the disease is Werner syndrome.