Oral Vit.D3/RA and CDCA/RA treated mice showed IL-2 response on day 21 PT (8.2 ± 0.39 and 7.0 ± 1.5 respectively), and these levels rose significantly on day 28 to 9.92 ± 1.08 and 7.45 ± 0.7 respectively (Fig. 3A) as compared to control group after 4 weeks of infection. Here, IL2 is linked to infection.