We initially analysed the expression of SNHG1 in The Cancer Genome Atlas (TCGA) (http://gepia.cancer-pku.cn/index.html) and found that SNHG1 expression was overexpressed in glioma compared to normal brain tissues (NBTs) (P < 0.0001) (Fig. 1a). Here, SNHG1 is linked to central nervous system cancer.