The experiment in nude mice showed that compared with mice in the NC siRNA+NS group, those in the ANRIL siRNA+NS, NC siRNA+cisplatin, and ANRIL siRNA+cisplatin groups were slowed down in tumor growth and reduced in tumor weight and the positive rate of HMGA2 (all P<0.05, Figure 6). Here, CDKN2B-AS1 is linked to neoplasm.