KLF6 and Hermansky-Pudlak syndrome: Based on previous studies demonstrating that induced KLF6 in ECs mediates vascular repair after injury (Gallardo-Vara et al., 2016; Garrido-Martín et al., 2013; Kojima et al., 2000), our results suggest that KLF6 may participate in pulmonary angiogenesis of HPS.