MALAT1 and endothelial dysfunction: Anotherfinding in the current study, was the link between positive family history for CADand MALAT1 levels, highlighting the presence of a genetic heritablefactor and suggesting MALAT1 as a putative risk factor for CAD.Moreover, the higher relative expression observed in CAD diabetic and hypertensivepatient subgroups suggest a possible role of these types of lncRNA in the mechanismsby which diabetes and hypertension produce endothelial dysfunction and acceleratethe rate of atherosclerosis (Dharmashankar andWidlansky, 2010; Kolluru etal., 2012).