ATXN3 and Machado-Joseph disease: Among compounds associated to symptomatic status of SCA3/MJD carriers, only serumneuron-specific enolase (NSE) levels and glutathione peroxidase activity(GSH-Px) were found to be related to SCA3/MJD by two independent case/controlstudies each (Tort et al.,2005; Zhou et al.,2011; Pacheco etal., 2013; de Assiset al., 2017).