IGF2BP3 and cancer: An IGF2BP3 mutation was found in a sample that also had drivermutations in PIK3CA and TP53. The protein productof IGF2BP3 is an RNA-binding factor that promotes cancer invasionby binding to transcripts that encode proteins, such as CD44, for functions relatedto cell migration, proliferation and adhesion (Ennajdaoui et al., 2016).