GPT and Hepatomegaly: Clinical and laboratory findings for the 180 patients with SD associated with having HLH, defined as an HScore probability of HLH of 70% or greater, included hepatomegaly (OR, 3.9; P = .015), peak AST (log U/L) (OR, 1.6; P = .0043), peak ALT (log U/L) (OR, 1.7; P = .0075), peak LDH (log U/L) (OR, 1.8; P = .010), and peak ferritin (log μg/L) (OR, 1.7; P = .048) levels, while increasing age at hospitalization (by 5-year increments) was negatively associated (OR, 0.8; P = .036) (Table 4).