These genes included CEBPB, BCL2, PAN2, NOS3, FTL, ARHGEF37, SMC3, EP300, JAK2, RPS6KA3, RPS6KA1, PRKACA, HIPK1, HIPK2, MAPK8, GSK3A, CLK2, and CDK3. It indicates that these CTS transcriptional signatures could be biomarkers for colon cancer relapse. The gene discussed is MAPK8; the disease is malignant colon neoplasm.