These genes included CEBPB, BCL2, PAN2, NOS3, FTL, ARHGEF37, SMC3, EP300, JAK2, RPS6KA3, RPS6KA1, PRKACA, HIPK1, HIPK2, MAPK8, GSK3A, CLK2, and CDK3. It indicates that these CTS transcriptional signatures could be biomarkers for colon cancer relapse. This evidence concerns the gene CDK3 and malignant colon neoplasm.