CDH1 and neoplasm: Despite no significant correlations with sex and age, we observed a significant negative correlation between E-cadherin expression and tumour differentiation, clinical stage, depth of invasion, lymph node metastasis, and vascular invasion (p < 0.05), Moreover, we found that the expression of E-cadherin was negatively correlated with tumour differentiation, especially between moderate differentiation and poor differentiation (p < 0.0125).