The average tumor size was significantly larger in patients with detectable plasma EGFR mutations compared to those without detectable plasma EGFR mutations (ARMS, 62.8 mm, 95% CI 43.1–82.5 mm vs. 32.8 mm, 95% CI 22.3–43.2 mm, p < 0.05; SABER/MassARRAY, 62.1 mm, 95% CI 40.3–83.9 mm vs. 31.4 mm, 95% CI 20.2–42.6 mm, p < 0.05) (Figure S3A,B). This evidence concerns the gene EGFR and neoplasm.