STK38 and hepatocellular carcinoma: Given that loss of hMOB2 can trigger a p53-dependent G1/S cell cycle arrest [37] and that NDR/LATS are associated with cell cycle progression [20,21], it will certainly be necessary to re-examine these HCC-based hMOB2 knockout cells to ensure the changes in NDR1/2, LATS1/2, and hMOB1 phosphorylation upon hMOB2 loss [62] are not merely reflecting indirect effects triggered by an underlying cell cycle arrest/delay.