In the myelodysplastic syndrome (MDS), the chronic myelomonocytic leukemia (CMML), and the acute myeloid leukemia (AML), increased PD-L1 levels were observed on CD34+ cells, whereas stroma/non-blast cellular compartment was positive for PD-1 [11]. This evidence concerns the gene CD34 and chronic myelomonocytic leukemia.