Reportedly, MZF‐1 could promote the proliferation of some cell types such as NIH3T3 fibroblasts and IL‐3‐dependent multipotent hematopoietic FDCP.1 cells;41, 45 however, several researchers also pointed out that MZF‐1 suppressed the proliferation of prostate cancer cells and colon cancer cells,46, 47 implying that MZF1 is a multifunctional protein and may play different roles in different cell types. Here, MZF1 is linked to malignant colon neoplasm.