SIRPA and cancer: It has been reported that miR‐133a may bind to the 3 prime untranslated region of CD47 mRNA, and contribute to the overexpression of CD47 in cancers.24 In numerous human‐derived xenograft murine models,25, 26, 27 blockage of the CD47/SIRPɑ axis using an antibody has been found to stimulate phagocytosis of cancer cells by macrophages in vitro and inhibit tumor growth in vivo.