CD40LG and endothelial dysfunction: Although we did not find significant differences between ACS and CG in sCD40L plasma levels, we observed that patients had higher levels of sCD40L and a positive linear correlation between sCD40L and IFN-γ was found (Figure 6); thus, it may be speculated that acute coronary event patients have enhanced T cell responses promoting endothelial dysfunction and systemic inflammation [43, 44].