GPT and Cirrhosis: In the present work, cirrhosis was induced by chronic administration of CCl4 in hamster, and the macroscopic and microscopic observations together with the markers of liver damage show cirrhotic animals with necrosis and fibrosis and lost hepatic functionality, whereas the placebo group did not return neither to characteristic cellular morphology nor to normal biochemical levels (glucose, albumin, total bilirubin, AST, and ALT).