Moreover, a predictive model based on a combination of the CXCL9 (MIG) and CXCL10 (IP-10) levels in serum was validated in an independent cohort of mice and selected as the best model; this model included a minimal set of biomarkers and enabled the identification of infections caused by S. pneumoniae or S. aureus. Here, CXCL10 is linked to infection.