According to the SDC1 staining intensity and the extent of positive tumor cells, our data showed that SDC1 was expressed at low levels in 29.4% (140/477) of CRCs, moderately expressed in 44.8% (228/477) of CRCs, and highly expressed in 22.8% (109/477) of CRCs (Table 1). This evidence concerns the gene SDC1 and neoplasm.