We selected gender, age, smoking, drinking, BMI, systolic blood pressure (SBP), diastolic blood pressure (DBP), serum glucose, TC, TG, high-density lipoprotein cholesterol (HDL-C); LDL-C, apolipoprotein (Apo)A1, ApoB, the relative expression of lncRNA TWF1, miR-126-5p, miR-142-3p and miR-369-3p were the best subset of risk factors to develop the CAD risk score and risk model (nomogram) (Fig. 6). The gene discussed is APOB; the disease is coronary artery disorder.